Interventions for sickle cell anemia treatment essay

Complications of priapism and treatment include bleeding from the holes placed in the penis as part of the aspiration or shunting procedures, infections, skin necrosis, damage or strictures of the urethra, fistulas, and impotence.

The total number of severe pain episodes in these patients 13, There have been many advances in treating pain, renal complications, Acute Chest Syndrome, and infections, and testing for Sickle Cell.

The spleen is enlarged Interventions for sickle cell anemia treatment essay of trapped blood and it causes circulatory problems and compromises. On the other hand, an individual with recessive homozygous trait carries a copy of the recessive alleles SS and therefore develops sickle cell shaped red blood cells.

Treatment should also include oxygen therapy with close monitoring for hypoxemia with continuous pulse oximetry or frequent assessment of blood gases. Their red blood cells, containing some abnormal hemoglobin, tend to sickle when they are infected by the malaria parasite.

Recent trials have shown that the susceptibility for septicemia with encapsulated organisms persists well into adulthood, and the benefit of continuing penicillin prophylaxis is now the subject of clinical research. Should the condition recur despite aspiration and local instillation of vasoactive drugs, consider shunting.

Low oxygen makes the red blood cells sickle. Risk for powerlessness related to illness-induced helplessness. Hematite, or blood in the urine, can occur with all types of sickle cell disease.

Vaso-Occlusive Crisis Management Vaso-occlusive crisis is treated with vigorous intravenous hydration and analgesics. In renal complications, the kidneys are prone to damage from the sickle cells. Erythrocytapheresis is now increasingly used as an alternative to simple transfusion. Intravenous fluids should be of sufficient quantity to correct dehydration and to replace continuing loss, both insensible and due to fever.

The sickle hemoglobin HbS gene is inherited in people of African descent and to a lesser extent in people from the Middle East, the Mediterranean area, and the aboriginal tribes in India.

Sickle-cell Disease

Researchers realized that where there was an endemic of malaria there was also a general population of people with the sickle cell trait hemoglobin S gene in the same geographical region. Elective laparoscopic cholecystectomy in a well-prepared patient has become the standard approach for symptomatic disease.

With the invasion of the malaria parasites in the bloodstream, red blood cells with the mutant haemoglobin die therefore traps the parasites within the red blood cells and reduce the chance of infection.

Morphine elixir can be used to control breakthrough pain. However, they can slightly suffer from sickle cell symptoms in low oxygen conditions for, instance in elevated heights. Many believe that lifelong transfusion therapy is necessary to completely eliminate recurrences in patients with SCD.

Demonstrates partially or completely sickled, crescent-shaped cells; anisocytosis; poikilocytosis; polychromasia; target cells; Howell-Jolly bodies; basophilic stippling; occasional nucleated RBCs normoblasts.

The AS heterozygote also has another major advantage and this is the ability to resist the protozoan parasite that causes anaemia.

Nursing Management Nursing management for a patient with sickle cell anemia focus on the following: Causes The causes of sickle cell anemia include: Begin at age 2 months with mg bid of penicillin V or G; at 3 years, increase the dose to mg bid.

Support groups are also useful. Sickle cell crisis occurs in people who have what is known as the Hemoglobin S gene HbSor more commonly the sickle cell trait. The randomized BABY HUG study has demonstrated that hydroxyurea hydroxycarbamide significantly reduces the incidence of vaso-occlusive crisis and dactylitis in very young children.

Because of the high RBC turnover, folate stores are often depleted. The sickle cells also block the flow of blood through vessels resulting in lung tissue damage acute chest syndromepain episodes arms, legs, chest and abdomenstroke and priapism painful prolonged erection. Saudi Arabia faces the need to apply and reinforce a control program that will prevent a generation of homozygosity recessive for sickle cell anaemia.

Patients with sickle cell anemia are unusually susceptible to infection, particularly pneumonia and osteomyelitis. Frequent blood transfusion is also necessary to prevent chances of stroke, pain crises and symptoms such as dizziness and breathlessness.

For episodes that last more than 2 hours, patients should go to the emergency department to receive intravenous hydration and parenteral analgesia. Usual doses for folic acid therapy are age based, as follows: Transfusion may accelerate healing.

Intensive care is indicated for patients in severe hypoxia or respiratory distress, as respiratory decompensation can rapidly require mechanical ventilation.

Essay Example: Interventions for Sickle Cell Anemia Treatment

Routine screening test that determines the presence of hemoglobin S HbS but does not differentiate between sickle cell anemia and trait. Other supportive measures include careful hydration.

The painful symptoms can occur in the bones, abdomen and chest and organs like the lungs, gall and spleen are severely affected. Additional factors contributing to pulmonary hypertension include older age, renal insufficiency, cardiovascular disease, cholestatic hepatopathy, systolic hypertension, high hemolytic markers, iron overload, and a history of priapism.This 1 OFF forms, or variants of Sickle Cell Anemia are homozygous (hemoglobin AS disease), doubly heterozygous sickle cell Page 3 hemoglobin C disease hemoglobin SC disease), and the sickle Beta-thalami’s” (Whether, p.

) Children and adults with homozygous sickle cell disease inherit a sickle cell (S) gene from each of their parents. Essay on Sickle Cell Anemia - Abstract Sickle Cell Anemia is a hereditary disease that changes the smallest and most important components of the body.

A gene causes the bone marrow in the body to make sickled shapes, when this happens; it causes the red blood cell to die faster. This is what causes Hemolytic Anemia. Essay The sickle cell disease is an inherited blood disorder that affects red blood cells. People with sickle cell have red blood cells that have mostly hemoglobin's, Sometimes these red blood cells become sickle-shaped or crescent shaped and have trouble going through small blood vessels.

Moreover, symptoms and signs of sickle cell disease generally occur during the period of early childhood. Characteristic traits of this particular illness take in a low number of RBC (i.e. anemia), frequent infections, and cyclic incidents of pain.

Sickle Cell Anemia Essay Sickle Cell Anemia Free Essay Examples Sickle cell disease or Sickle cell anaemia (SCA) is a type of anaemia where the red blood cells acquire a sickle shape because the protein haemoglobin in the cells is abnormal.

Sep 04,  · TWiTCH was conducted in high-risk children with sickle cell anemia and TCD velocities ≥ cm/s who had received at least 1 year of transfusions and had no severe vasculopathy identified on magnetic resonance angiography.

Weiner D, et al. Nitric oxide for inhalation in the acute treatment of sickle cell pain crisis: a.

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